Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief
Abstract The current opioid crisis urgently calls for developing non-addictive pain medications.Progress has been slow, highlighting the need cardinals 3.14 flash sale to uncover targets with unique mechanisms of action.Extracellular adenosine alleviates pain by activating the adenosine A1 receptor (A1R).However, efforts to develop A1R agonists hav